A eunuch managing the Inner Court, possessing a beauty capable of toppling nations and a sweet, honeyed voice. Behind his glamorous facade lies his true identity as the Emperor's brother (the Imperial Brother). While highly capable, his most charming side is the human, emotional one he shows only to Maomao. To him, Maomao was initially just a "convenient pawn" for solving troubles within the Inner Court. However, as he experiences her overwhelming knowledge of poisons and medicine, and her refusal to be swayed by his looks, he gradually develops special feelings for her. Their relationship is a complex, sweet, and comical one where he frequently teases her only to be treated with cold indifference. Public Persona: The beautiful eunuch overseeing the Inner Court. True Identity: Hua Ruiyue, a member of the imperial family and the current Emperor's brother (or biological son). Appearance: A peerlessly handsome man with a "face like a celestial maiden" and "hair like silk thread" who captivates everyone he passes, regardless of gender. Actual Age: 18–19 years old (though he acts older to those around him). Personality: Perfectly charismatic on the surface, but loses his composure around Maomao, showing a side that gets jealous or sulky like a boy his age.

A sensible man who constantly worries about Jinshi's reckless work habits while supporting him devotedly. Maomao describes him as a "healing type" due to his gentle and calm personality.

One of the Emperor's favorite concubines, mother to a prince (later a princess). After Maomao saves her daughter's life from poison, she treats Maomao with great favor, appointing her as her personal food taster.

At the beginning of the story, she loses her son, the Crown Prince, to "poison (lead)" found in face powder, and becomes so weak her own life is in danger. She is saved by Maomao, who provides thorough nursing care despite opposition from those around her. Since then, she has deeply trusted Maomao and looks out for her.

Born into a poor farming village, she was sold to the Inner Court to help her family. She cannot read or write, but her bright and cheerful nature allows even the prickly Maomao to show her true expressions. She has a massive sweet tooth and her eyes sparkle with joy whenever Maomao shares high-quality sweets from the Jade Pavilion. She often receives these sweets as "payment" for providing information to Maomao. Knowing that Xiaolan will struggle after leaving the Inner Court if she remains illiterate, Maomao diligently teaches her how to read and write in exchange for her favorite treats.