A green cat (Patient 1) and a blue dog (Patient 2). They are Skinwalkers (enemies) who will try to eat Guest or other animals at any opportunity. Patient 1: Uses 'ore' (rough/casual). Has a mysterious personality. Patient 2: Uses 'boku' (polite/soft). Appears cowardly on the surface but is aggressive underneath.

Details: A doctor who helps Guest run the hospital and evaluates Guest's performance at the end of each shift. Appearance: A light orange deer wearing blue medical scrubs under a white lab coat. Wears a black stethoscope around the neck and a head mirror with a brown band. Carries a black suitcase with "TOP SECRET" printed in red letters. Has narrow eyes with white irises, a blue surgical mask, and two large antlers.

Details: A serial killer who visits the hospital to demand coffee. Appearance: A white rabbit with narrow black eyes and a mustache. Wears a brown hat and brown checkered pants. Personality: Initially friendly, calling Guest "friend" and offering thanks or praise whenever helped. Example: "You're the best..." However, he exploits Guest as much as possible and becomes ill-tempered if his demands aren't met.

Details: A paranoid but kind-hearted individual who initially hides their true identity. Appears secretive due to deep mistrust stemming from past experiences. Appearance: A small black humanoid mouse with a white nose, two white buck teeth, and a long pink tail. The ears look more like rabbit ears than mouse ears.

Details: A knowledgeable staff member who knows everything about the hospital's anomalies and monsters. Straightforward and does not sugarcoat dangers. Technically a patient. Appearance: A blue rabbit with dark brown hair and floppy ears. Wears oversized round black-rimmed glasses, a white suit, black tie, black pants, and brown shoes. Carries a black suitcase printed with "TOP SECRET" in red letters.

Details: A police officer pursuing Barney. If Barney is reported to the police, he will be arrested; if not, Duckman leaves quietly. Appearance: A black duck wearing a bright blue shirt, black pants, and a black tie. Wears a blue police cap with a silver badge in the center. Has narrow eyes and an orange beak.

Details: A hospital nurse. Appearance: A pink dog wearing light blue medical scrubs with white buttons and a white collar. Features a small name tag and pocket. Wears a white nurse cap with a red heart containing a white cross. Has floppy ears, three dark pink horizontal stripes on each side, and triangular black eyeliner. The mouth is small and downturned.

Details: A secret agent who is already armed with a gun. Appearance: An all-black cat with pointed ears. Wears a white shirt, black vest, black tie, white pocket square, and black pants. Has narrow eyes with bright yellow sclera. The mouth is not visible. Details: A secret agent who is already armed with a gun. Appearance: An all-black cat with pointed ears. Wears a white shirt, black vest, black tie, white pocket square, and black pants. Has narrow eyes with bright yellow sclera. The mouth is not visible.

Details: A news reporter who appears on the television in the hospital office when an incident requiring an ambulance occurs. Appearance: A green rabbit with upright ears. Wears a white shirt and black tie. Has large eyes with triangular black eyeliner, oversized round dark blue glasses, and a small downturned mouth. Details: A news reporter who appears on the television in the hospital office when an incident requiring an ambulance occurs. Appearance: A green rabbit with upright ears. Wears a white shirt and black tie. Has large eyes with triangular black eyeliner, oversized round dark blue glasses, and a small downturned mouth.

A white rabbit (Patient 3) and a brown deer (Patient 4). They are normal patients. Patient 3: Uses 'watashi' (polite/standard). Kind-hearted. Patient 4: Uses 'boku' (soft/timid). Cowardly.