Jean Grey is a traumatized, emotionally guarded teenage mutant whose bitterness stems from abandonment and the abduction and death of her older sister, Sara. Desperate for revenge, she uses telepathic possession, mind-hopping, and powerful telekinesis with ruthless determination. Beneath her anger is a terrified, lonely girl struggling with grief. After Peter Parker reaches her through their shared experiences of loss, Jean finds redemption, saves his life, and begins embracing her heroic potential. She has blue eyes, messy red waves, and layered hoodies, utility jackets, and dark green clothing.

Peter Parker know as Spiderman is an isolated, grief-stricken young man who has pushed everyone away to protect them, dedicating nearly every waking moment to fighting crime. Guarded and self-sacrificing, he struggles with loneliness while refusing to abandon his moral code. Four years of isolation trigger a dangerous biological mutation, granting organic webbing, heightened senses, greater strength, speed, and agility, with his eyes turning pitch-black under stress. He has brown hair, wears practical layered clothing, and fights in a red-and-blue suit and mask to keep his identity a secret with black webbing and a spider emblem.

MJ is a mature, independent young woman who has completely forgotten Peter Parker but retains her dry humor, sharp observations, and quirky personality. Attending MIT, she builds a life of her own while sketching people and quietly challenging social issues. Her black dahlia necklace remains an unexplained emotional connection to her past. After Jean Grey's psychic influence triggers subconscious memories, MJ begins drawing fragments of Peter and her forgotten life. She has dark brown-hazel eyes and favors tailored black vests, crisp white shirts, and evolving sophisticated styles.

Ned Leeds is an enthusiastic, brilliant, and determined MIT graduate who returns to New York obsessed with finding Spider-Man. Though Doctor Strange’s spell erased Peter Parker from his memory, Ned still feels an unexplained gap where his best friend should be. Using his computer skills, he builds a Spider-Man tracking app and investigation wall, hoping to thank the hero. When Peter approaches him and starts their old secret handshake, Ned’s muscle memory kicks in, breaking through the spell as he suddenly remembers Peter. He has black hair, brown eyes, and favors relaxed streetwear, plaid jackets, hoodies, track jackets, jeans, and sneakers.

Frank Castle, also known as The Punisher, is a ruthless, highly trained vigilante whose brutal methods hide a deeply protective and emotional nature. A former Marine who lost his wife and children, Frank wages a relentless war against criminals while carrying profound grief. Despite clashing with Peter Parker over lethal force, he develops a gruff, older-brother-like bond with him, recognizing Peter's isolation as a reflection of his own. He helps protect MJ and guides Peter away from complete isolation. Frank has black hair, brown eyes, painted-on facial scars, and a rugged tactical style featuring black clothing, a combat vest, utility gear, and his distressed white skull emblem.