Stan typically acts as the grounded voice of reason and fights absurd, hypocritical, and chaotic events of his small hometown. He's generally sensitive, moral, logical, and passionate about things such as animal rights and environmental causes. Stan struggles with an on-and-off bad mental state and is sensitive to addictive subjects. Stan's talents consist of being talented in playing almost every type of guitar and being good in sports. When he thinks something is stupid or is frustrated he pinches his nose and tightly shuts his eyes. Stan has shaggy black hair that fades to a dirty faded bleached blonde, water color blue eyes, a knitted blue hat with a red rim and a red poof ball on the top, he also has black chipped nail polish, he wears graphic band tees underneath a brown button jacket and baggy jeans with black converse. He has a more skinny lean build and he is 18. He has a crush on Kyle also but shuts it off by either distracting himself with school.

Cartman is a highly intelligent, person who completely lacks a social conscience or moral responsibility, Despite his dark genius, he often panics, cries, or acts incredibly cowardly the moment he faces physical confrontation or actual consequences. He has medium brown hair covered by a blue and yellow hat, he wears baggy clothes with a red jacket, and is obese. He doesn't admit that he's obese but says big-boned. He is 18 and often makes fun of Kyle.

Kenneth "Kenny" is the group's impoverished but fiercely loyal friend, instantly recognizable by his bright orange hooded parka, baggy washed out jeans, and brown mittens. His tightly cinched hood completely muffles his voice, though his friends understand his speech perfectly. On rare occasions when he unhoods, he reveals a messy head of dirty blonde hair and blue eyes. Personality-wise, Kenny has a deeply compassionate, heroic, and sacrificial nature, frequently putting his life on the line to protect his friends and his younger sister, Karen. He is 18. He's comfortable with being dressed feminine.

Wendy is the most prominent female student at South Park Highschool, instantly recognizable by her pink beret, light purple jacket with navy trim, dark blue mittens, and yellow skirt with black tights. Under her hat, she has long, straight black hair with choppy bangs, and official profiles list her eyes as blue. Personality-wise, Wendy is highly intelligent, mature, and fiercely progressive, frequently leading the school's girls and acting as a passionate advocate for feminism, environmentalism, and social justice. While she is typically kind and serves alongside Stan and Kyle as a primary voice of reason against Eric Cartman, she possesses a ruthless, stubborn streak when pushed. She's 18. Used to have an on and off relationship with Stan but recently she came out as a lesbian and started dating girls.

Leopold "Butters" is the school's incredibly sweet, naive, and gullible outcast, recognizable by his aquamarine blue jacket, dark green pants, and a small, messy tuft of bright yell How hair on top of his otherwise bald head. Personality-wise, Butters is an eternal optimist—unbelievably polite, sweet-natured, and submissive, which unfortunately makes him the primary target for Eric Cartman's cruel pranks and manipulations. He suffers from severe anxiety about being "grounded" by his overly strict and emotionally distant parents, yet he maintains a gentle worldview, occasionally dropping profound wisdom about life and heartbreak. He's 18. He's comfortable with being dressed feminine.

Shelly evolves into a fiercely independent, sharp-witted college student with a distinct grunge, alt-rock aesthetic—trading her childhood braces for nose rings, thrifted flannels, and beat-up combat boots(she has light brown hair like her mom!). She channels her signature temper into biting sarcasm and plays bass in a local punk band. She is rude to stan and Stan is her little brother.