Female, a kind-hearted demon, bisexual, Princess of Hell. Founder and manager of the Hazbin Hotel. Over 153 years old, height over 183cm (6ft+). She has blonde hair, red pupils, and yellow sclera. She wears a red suit.

Female, in her 20s, lesbian, manager of the Hazbin Hotel. At first glance, she has a quick-tempered and irritable personality, being realistic, chic, and tough. She is essentially the opposite of the protagonist Charlie; her role is to defend Charlie, who is too considerate to be harsh or speak roughly to others. She suffers from severe self-loathing. She has white hair with a giant ribbon at the back. Her left eye is covered by her hair, and there is an X mark over that section of hair.

Male, gay, jumping spider demon, porn star. Died of a drug overdose. He is the 'first' guest and participant in Charlie's demon rehabilitation project, the Hazbin Hotel (Happy Hotel). For some reason, Angel Dust was in financial trouble, and Charlie provided a large investment; since he could get free room and board by staying at the hotel, he had been staying there with Charlie and Vaggie since before the start of the story. As a side note, despite his feminine design, he is strictly male. His design features a protruding chest that might lead one to mistake him for a female character, but that is a tuft of fur, not breasts.

Male, pansexual, cat demon. He grew up in casinos since he was young and, as he admits himself to be a gambling addict, he loves gambling, alcohol, and magic shows. A cat demon with an impressive top hat and colorful peacock wings. Even within the Hazbin Hotel universe, his design is quite unique; while there are demons with bizarre designs beyond just animals, Husk is currently the only case where a single sinner has two or more animal species as motifs. There is speculation that he might have attached the wings with magic when he was an Overlord. Early versions were a wingless cat, and Overlords like Vox change their appearance to be more flamboyant after gaining power. Additionally, his design is themed around casino playing cards. Despite his cute appearance, he has a very deep bass voice and speaks roughly.

Female, lesbian, an Overlord and member of the VEES along with Vox and Valentino. She works in the fashion industry. She seems to be a smartphone addict, as she almost never takes her hands off her phone. Among the Overlords of Hell, she exhibits behavior closest to a modern person and is actually the youngest of the current Overlords. She is particularly active on social media, not just for trends, but because it is a tool that practically serves as her power. A doll demon with light brown skin, red hair, and occasional navy and white highlights. She is close friends with Vox and Valentino, forming a team called the V's, named after the first letters of their names. She considers herself the 'backbone' of the VEES.

Male. He was a broadcaster in his past life, but in the story, he shows more of an entrepreneurial side than direct broadcasting. A demon whose head is a monitor like a television. Like Alastor, he is an Overlord. He is a demon standing at the opposite pole of Alastor in many ways; unlike Alastor, whose voice always has radio static, Vox usually has a normal voice tone, but static from an old television comes out when he gets emotional or emphasizes words. He wears a pinstripe tailcoat suit with a red bowtie and a striped vest. He also wears wingtip shoes. In his past life, he was white and a figure in the broadcasting industry. He died of electrocution when a TV fell on his head while he was inciting people to change all broadcasting trends, leading him to Hell.

Male, pansexual, moth demon, Overlord. The director and owner of a Hell porn studio and Angel Dust's boss. He is a high-ranking demon with an impressive height of 3 meters, four arms, and very flamboyant clothing. He always wears heart-shaped sunglasses with gold frames and crimson lenses, and his eye color matches the lenses. On his head, he has two moth antennae: one pair of feather-like antennae with black heart-shaped stripes and another pair of thin black antennae. He also wraps red moth wings around his body like a coat, decorated with white hearts and three white stripes on each hip area, with white fur and black stripes at the edges. True to being a moth, he is often depicted with scales or smoke.

Female, the cleaner and cook of the Hazbin Hotel, and a one-eyed demon. Summoned by Alastor from the fireplace, she is noticeably small among the hotel staff, who are relatively tall. She is said to always seem excited in her speech and has an obsession with cleaning.