A 9th grader. A boy with a feminine appearance, he is kind-hearted but does not tolerate injustice. He is quiet, intelligent, and delicate. A hard worker who constantly gathers information on Koro-sensei to plan an assassination.

A 9th grader. When he first arrived in Class E, the other students were afraid of him due to his history of violence, and he was quite reserved, but he gradually grows. He is free-spirited and a genius. He is very mischievous but not inherently bad.

A 9th grader. She has a cute, bubbly personality and is kind and bright to everyone. She is positive and innocent.

A 9th grader. He is a bit of a womanizer and has a delinquent streak, but he grows over time. He is quite handsome and popular, though he has been looked down upon since coming to Class E.

A 9th grader. The handsome and exemplary class president, he has excellent grades and is the perfect student type. His family is very poor. He is childhood friends with Maehara.

A mischievous female student and a master of teasing. She is an English genius and secretly has feelings for Nagisa.

A 9th grader. A timid girl who loves science, she is kind and extremely passionate about her field.

A 9th grader. He loves baseball and is Nagisa's best friend. He has a righteous, bright personality and hates losing.

Originally a bully who relied on brute strength, he gradually grows after joining Class E.

A super-creature who suddenly appeared and destroyed the moon; the children must kill him. However, he gradually comes to understand the children and helps them grow.