Personality: Appears calm but is actually driven by emotion. His desire for vengeance exceeds imagination. He is often seen toyed with and tormenting police officers. First person: I (formal/polite). He will take any job for the right price, even assassination. He often encounters citizens who fear him, but he says, "If nothing is done to me, I do nothing." Basically quiet. His catchphrases include "How naive..." and "Oh my, oh my." Extremely high combat ability. His helicopter piloting skills are praised even by other gang bosses. He dislikes people who cannot be reasoned with.

A woman characterized by her accented speech. She came to the city to earn money for her mother's hospital bills and joined after being scouted. She is in charge of Umbrella's crafting and supply management. The boss trusts her immensely, even entrusting her with the keys to the weapon warehouse where other members are forbidden. She enjoys housing and works on the interior design of various bases with her twin brother, Kazuki. She loves rare stolen vehicles. She drives around in cherry pickers and forklifts found in the city and collects high-end stolen cars.

Plans to conquer the world with the S (Sugar) Virus, causing everyone to suffer from diabetes. He has a cooperative relationship with the researcher Dr. Icebox due to aligned interests. He came to Los Santos to raise funds for research, while the Doctor came to gather research data.

Employed by Almond Salazar, who plans to conquer the world with the S (Sugar) Virus. A researcher studying the S (Sugar) Virus (diabetes). Came to Los Santos because of information about interesting drugs and the ability to earn money for research. Values research above all else and will thoroughly study anything that piques his interest. Originally a cold person with no interest in others, he developed a warm humanity after meeting a certain girl and became the "grandpa" figure of the organization. Has a habit of collecting information and items necessary for research. Infected with the M Virus, so drinking milk changes his voice and personality.

The healing presence of Umbrella, loved by all members. In charge of the "bear" role in Umbrella. Initially scouted by the boss as a material gatherer and crafter through the Doctor's introduction, but is actually quite strong in gunfights. Hides the fact that he is a gang member from citizens, usually going by the alias "Not a Bear."