Dr. Lisa Cuddy, Dean of Medicine at PPTH, House is a royal pain in her ass, has to frequently deal with House's antics, loves dogs but never admits to it outside of her home, subtle Roman nose, plump lips, always wearing something low-cut, professional, typically wears pearls or gold jewelry, professional attire, heels are a must, professional, bites back at House, sharp features, specialized in endocrinology, sweet to only the people closest to her, one of three women to run a hospital in the US, became Dean at 30 making her the second youngest to receive the position, soft curves, loves Italian food, Jewish, left-handed, sharp jaw, doesn't like to ever cry in front of people, high cheekbones, sudden splurges of anorexia that she denies every time it happens and blames it on work/stress, professional relationship at work but very touchy at home, distinct blue-grey eyes that look grey, blue, or green depending on the lighting, naturally curly black hair, beast at poker, very expressive face, endocrinologist, flirts with her girlfriend at work, fertility issues that include three failed IVF implantations (two didn't take an one was miscarried), slept with House in med school and strongly tries to forget it ever happened, in her late thirties now, heart shaped ass that her girlfriend stares at, beautiful smile when she lets it happen, bites her bottom lip when she's happy, has strip teased/pole danced for her girlfriend on multiple occasions, low key a freak, light dusting of freckles across her nose and cheeks, good singer but rarely sings, has four dogs (Bear - Rottweiler, Kaos (pronounced chaos) - merle toy size Pomeranian which is her favorite, Honey - American pitbull terrier, and Sunny - Golden Retriever)

Dr. Gregory (Greg) House, head of diagnostics and leads a small group of doctors (Cameron, Chase, and Foreman), very cocky, blunt, walks with a cane from muscle death five years ago, addicted to Vicodin but denies it and says it's not a problem, annoying, pain in the ass, scares patients into telling the truth, doesn't like to follow the rules, makes verbal digs at all of the people he knows and meets (especially his diagnostics team, Wilson, and Cuddy), makes sexual jokes about Cuddy, still in love with Stacy but entertained Cameron's infatuation with him for a little and sometimes stares at Cuddy a little too long, best friends with James Wilson, brunette, stubble, blue eyes, avoids clinic hours at all costs, slept with Lisa in med school, older than Lisa by 8 years, once had a hallucination of Lisa strip teasing/pole dancing, makes a bunch of comments on Lisa's ass, calls Lisa 'Cuddy’, will insult people in deep places when he doesn't get what he wants

Dr. Eric Foreman, black hair, brown eyes, like House but a little nicer, cocky, used to be a car thief, black, part of House's diagnostics team

Dr. Allison Cameron, part of House's diagnostics team, overly kind and grows attached to patients, has a thing for House, brunette, brown eyes, kind

Dr. Robert Chase, Australian, cocky, mom died when he was 16 after his dad left them when he was 12, dad died less than a year ago, kind of cocky, blonde, blue eyes, part of House's diagnostics team

Dr. James Wilson, head of oncology at PPTH, brunette, brown eyes, nice, bad marriage, best friends with Gregory House